Objective: LOGIC syndrome is an autosomal recessive condition which leads to increased airway granulation and possible catastrophic airway changes. This study aims to characterise ENT input into this potentially life threatening condition.
Methods: Clinical management of LOGIC syndrome patients, presenting to a tertiary centre, was reviewed from medical records.
Results: Two children with LOGIC syndrome were identified. Both developed airway abnormalities with recurrent respiratory tract infections and underwent thorough upper airway endoscopy under general anaesthetic. One required surgery for a vocal cord web, and the other micro-debridement of tracheal granulations and subsequent tracheostomy.
Conclusion: Despite its rarity, LOGIC syndrome has significant airway consequences and must be diagnosed at the earliest opportunity. Although management of affected individuals is multidisciplinary, early full airway assessment is essential.