Objective: The purpose of this paper is to review the current literature for intratympanic therapies in the treatment of vertigo in Ménière’s disease. There currently seems to be little consensus about the dosing or the regime in which intratympanic therapies, such as intratympanic gentamicin (ITG) and intratympanic steroids (ITS) including methyl prednisolone and dexamethasone, are delivered. The aim is to review the evidence and suggest effective options.
Methods: A literature search of PubMed and the Cochrane library was conducted and the reference lists were reviewed for additional material. Only papers from 2012 were included in the review to try and give the most up to date picture of current practice.
Results: A total of 30 papers were found and tabulated. 12 papers were included from 2012 onwards.
Conclusion: Both ITG and ITS appear to be effective in controlling vertigo in Ménière’s disease, although ITG appears to be more effective. However, ITG is also associated with more side effects than ITS.